Blood Work – June 2, 2011

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As always, you can find the record of my blood work history – from July 2001 to present – in this Hormone Table.

Blood was drawn on a Thursday morning prior to my weekly meds so I should have had the least bit of Cabergoline in me as possible. 

I continue to take .25 mg of Cabergoline weekly. I’ve been taking a vitamin B supplement and I’d taken the vitamin a couple of hours before my blood draw.

I weighed 299 pounds, which puts me up 10 pounds from last visit. Yes, yes, yes… I keep talking about needing to lose weight but that’s all I’m doing – talking about it. I’ve got no sense that I’m seriously trying to lose weight and having no luck at it. 

Hormone Info
Prolactin: 8.5 (4.0-15.2)

Regarding Vitamin B6

Effect of pyridoxine on human hypophyseal trophic hormone release: a possible stimulation of hypothalamic dopaminergic pathway

Delitala G, Masala A, Alagna S, Devilla L.

Abstract

A single dose of pyridoxine (300 mg iv) produced significant rises in peak levels of immunoreactive growth hormone GH and significant decrease of plasma prolactin PRL in 8 hospitalized healthy subjects. Serum glucose, luteinizing hormone LH, follicle stimulating hormone FSH and thyrotropin TSH were not altered significantly. In addition, in 5 acromegalic patients who were studied with both L-dopa and pyridoxine, inhibition of GH secretion followed either agent in a similar pattern. These data suggest a hypothalamic dopaminergic effect of pyridoxine.

and

Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in growth hormone induced by exercise
Barletta C, Sellini M, Bartoli A, Bigi C, Buzzetti R, Giovannini C.

The influence of vitamin B6 in a dosage of 300 mg X 2 in 24 hrs, on circadian rhythm of plasmatic ACTH, cortisol, prolactin and somatotropin have been studied in 10 normal women. After vitamin B6 24 hrs pattern of ACTH and cortisol is unchanged; prolactin levels are slightly lower, in a statistically unsignificant proportion the night peak of growth hormone is higher in a statistically significant proportion (p. 0.05). The effect of vitamin B6 is likely to me mediated by dopaminergic receptors at hypothalamic level as previous studies by other Authors appear to prove.

Boll Soc Ital Biol Sper 1984 Feb 28;60(2):273-8
N Engl J Med. 1982 Aug 12;307(7):444-5.